Second-degree atrioventricular block as an early manifestation of adult systemic lupus erythematosus.

Oral contraceptive-related transverse sinus thrombosis as an initial manifestation of antiphospholipid syndrome in the absence of systemic lupus erythematosus

Neonatal congenital heart block.

Congenital Heart Block (CHB) is the most serious complication of neonatal lupus erythematosus. Transplasental transfer of maternal anti SSA/Ro or antiSSB/La antibodies around 12th week of gestation is associated with development of CHB. This may lead to inflammation, fibrosis and scarring of fetal conduction system in the early second trimester. Different degrees of atrioventricular (AV) block ...

Hematologic manifestation of systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease. The most common hematologic finding is anemia, leukopenia, thrombocytopenia and secondary antiphospholipid syndrome with recurrent abortion and thrombosis. The autoimmune fibrosis of bone marrow is another manifestation of autoimmune disease especially SLE, that must be correctly differentiated from primary myelofibrosis.

PSEUDO TUMOR CEREBRI AS THE MAJOR MANIFESTATION OF SYSTEMIC LUPUS ER Y THEMATOSUS IN A CASE OF FEVER OF UNDE TERMINED ORIGIN

Systemic lupus erythematosus (SLE) is less likely to present as fever of undetermined origin today. This is due to the widespread use of immunologic tests which permit early diagnosis. It is not surprising therefore that only atypical cases of SLE present as FUa. Although uncommon, pseudotumor cerebri has been recognized as either a presenting manifestation or a complication of SLE. This c...

Atrioventricular conduction in children of women with systemic lupus erythematosus.

The neonatal lupus syndrome consists of transient cutaneous lupus lesions or permanent congenital complete heart block (or hepatic fibrosis), or both, in infants born to mothers with systemic lupus erythematosus (SLE). The frequency of conduction abnormalities was examined in 86 offspring of 53 women affected by SLE. Electrocardiograms from the offspring demonstrated normal sinus rhythm in 84 o...